Biological Engineering

“Junk” DNA plays a key role in speciation

Researchers propose a new framework for how satellite DNA, sometimes called “genomic junk,” is essential in the organization of chromosomes in cells. They suggest this quickly-evolving DNA is one reason different species are unable to successfully interbreed.

LiftPose3D: Turning 2D images into 3D models

EPFL scientists have developed a deep learning-based method called LiftPose3D, which can reconstruct 3D animal poses using only 2D poses from one camera. This method will have impact in neuroscience and bioinspired robotics.

Organoid bladders reveal secrets of UTIs

Scientists at EPFL have developed two complementary bladder models to study urinary tract infections (UTIs) caused by E. coli: bladder organoids and a bladder-on-a-chip. The two studies reveal how bacteria invade the bladder, and how they evade the immune system and resist antibiotics.

Brain fingerprints help doctors detect neurological disease

An EPFL scientist has found that brain fingerprints – or maps of the neural connections within our brain – can be used to detect a decline in cognitive ability. That’s because the fingerprints are harder to detect in people who already have mild cognitive impairment.

Next-generation implants will be biodegradable and non-invasive

EPFL engineers have developed a neural interface that disappears harmlessly in the body after several months and allows natural tissue to grow back. What’s more, it can be implanted in a patient’s blood vessel rather than inside the brain, thereby avoiding the need for invasive surgery.

Engineered protein gives an energetic boost to cancer-fighting cells

EPFL scientists have discovered that an engineered interleukin-10-Fc fusion protein can boost the effectiveness of exhausted T lymphocytes – our body’s immune cells for fighting cancer, by reprograming their metabolism.

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